| Premier Inn, Glasgow Cambusland/M74, J2A) | M74, Junction 2a,3 | Family Rooms Table Table Free Car Park Meeting Rooms | 0.5 Miles (3 Mins) from Junction 2a,3 |
| Premier Inn, Glasgow East | M74, Junction 3a | Family Rooms Accessible Rooms Beefeater Free Car Park | 0.3 Miles (2 Mins) from Junction 3a |
| Holiday Inn Express, Strathclyde Park | M74, Junction 5 | Bar Restaurant Meeting Rooms
| 0.3 Miles (1 Min) from Junction 5 |
| Inn Keeper's Lodge, Strathclyde Park | M74, Junction 5 | Toby Carvery Free WiFi Family Rooms Accessible Rooms | 0.3 Miles (1 Min) from Junction 5 |
| Bothwell Bridge Hotel, | M74, Junction 5 | Restaurant Bar Family Rooms Meeting Rooms | 1.6 Miles (4 Mins) from Junction 5 |
| Holiday Inn Express, Hamilton | M74, Junction 6 | Bar Meeting Rooms
| 0.8 Miles (2 Mins) from Junction 6 |
| Moorings Hotel - Motherwell, | M74, Junction 6 | Restaurant Bar Free WiFi
| 1.6 Miles (3 Mins) from Junction 6 |
| Hillcrest Guest House - Motherwell, | M74, Junction 6 | - | 1.6 Miles (4 Mins) from Junction 6 |
| Strathclyde Guest House, | M74, Junction 6 | - | 1.6 Miles (4 Mins) from Junction 6 |
| Shawlands Park Hotel, | M74, Junction 8 | Restaurant Bar Meeting Rooms
| 0.9 Miles (2 Mins) from Junction 8 |
| The Old School Guest House, | M74, Junction 8 | Family Rooms Accessible Room En-suite Facilities
| 0.4 Miles (1 Min) from Junction 8 |
| Abington Hotel, | M74, Junction 13 | Restaurant Family Rooms En-suite Facilities
| 1.0 Mile (3 Mins) from Junction 13 |
| Crawford Arms Hotel, | M74, Junction 14 | Bar
| 1.5 Miles (4 Mins) from Junction 14 |
| Holmlands Country House, | M74, Junction 14 | En-suite Facilities
| 2.5 Miles (6 Mins) from Junction 14 |
| Best Western, Moffat House Hotel | M74, Junction 15 | Restaurant Bar Family Rooms Meeting Rooms | 1.7 Miles (3 Mins) from Junction 15 |
| The Stag Hotel - Moffat, | M74, Junction 15 | Restaurant Bar Free WiFi
| 1.7 Miles (3 Mins) from Junction 15 |
| Annandale Arms Hotel, | M74, Junction 15 | Restaurant Bar Free WiFi
| 1.7 Miles (3 Mins) from Junction 15 |
| Buccleuch Arms Hotel, | M74, Junction 15 | Restaurant Bar Family Rooms Meeting Rooms | 1.6 Miles (3 Mins) from Junction 15 |
| The Famous Star Hotel, | M74, Junction 15 | Restaurant Bar Family Rooms Free WiFi | 1.6 Miles (5 Mins) from Junction 15 |
| Lochhouse Farm b&b, | M74, Junction 15 | Family Room Accessible Room
| 0.5 Miles (2 Mins) from Junction 15 |
| The Old Stables Inn - Beattock, | M74, Junction 15 | Family Room En-suite Facilities
| 0.8 Miles (3 Mins) from Junction 15 |
| Townhead Hotel, | M74, Junction 17,18 | - | 1.0 Mile (3 Mins) from Junction 17,18 |
| Somerton House Hotel, | M74, Junction 17,18 | Restaurant Bar Meeting Rooms
| 2.3 Miles (5 Mins) from Junction 17,18 |
| Best Western, Dryfesdale Country House Hotel | M74, Junction 17,18 | Restaurant Bar Free WiFi
| 0.7 Miles (2 Mins) from Junction 17,18 |
| Ravenshill House Hotel, | M74, Junction 17,18 | Garden Dining Room Bar
| 1.6 Miles (5 Mins) from Junction 17,18 |
| The Queens Hotel - Lockerbie, | M74, Junction 17,18 | Lounge Bar
| 2.1 Miles (5 Mins) from Junction 17,18 |
| Kirkconnel Hall Hotel, | M74, Junction 19 | En-suite Facilities Restaurant Bar Meeting Rooms | 0.2 Miles (1 Min) from Junction 19 |
| Ecclefechan Hotel, | M74, Junction 19 | Bar Dining Room Family Rooms
| 0.6 Miles (2 Mins) from Junction 19 |
| Smiths Hotel at Gretna Green, | M74, Junction 22 | Restaurant Bar Family Rooms Meeting Rooms | 0.9 Miles (2 Mins) from Junction 22 |
| Hazeldene Hotel - Gretna, | M74, Junction 22 | Restaurant Bar
| 0.4 Miles (1 Min) from Junction 22 |